What are the advantages of loxoprofen sodium?

Loxoprofen sodium has an excellent analgesic, anti-inflammatory and fever-reducing effects, and its analgesic effect is especially powerful.1
Loxoprofen sodium has a rapid analgesic effect starting after only 15 minutes.2
Available in two forms (Tape and Tablets).3
Loxoprofen sodium is well tolerated in clinical trials.4

Reasons to use Roxonin® Tapes

Topical analgesics offer similar efficacy to the oral route with less side effects.5
The use of patches is preferred by many patients
because it’s more convenient to apply to the skin than
using gels.6


  1. Helmy SA. Pharmacokinetics and Bioequivalence Evaluation of 2 Loxoprofen Tablets in Healthy Egyptian Male Volunteers. Clin Pharmacol Drug Dev. 2013;2(2):173-7.
  2. Uchida Y, et al. Clinical evaluation of CS-600 (Loxoprofen sodium) on postexodontic pain. Oral Therapeutics and Pharmacology 1984;3(1):32-48.
  3. Roxonin® PIL.
  4. Aoki, T. Effectiveness and Safety of Loxoprofen in Elderly Patients with Lumbar Pain. Drug Invest 1992;4:477–483.
  5. Zhao D, Chen Z, Hu S, et al. Efficacy and Safety of Loxoprofen Hydrogel Transdermal Patch Versus Loxoprofen Tablet in Chinese Patients with Myalgia: A Double-Blind, Double-Dummy, Parallel-Group, Randomized, Controlled, Non-Inferiority Trial. Clin Drug Investig. 2019;39(4):369-377.
  6. Mazières B, Rouanet S, Velicy J, Scarsi C, Reiner V. Topical ketoprofen patch (100 mg) for the treatment of ankle sprain: a randomized, double-blind, placebo-controlled study. Am J Sports Med. 2005;33(4):515-23.